Major Research Findings

  • WGS surveillance of AMR pathogens from retail markets of Assam was carried out. The occurrence of methicillin-resistant Staphylococcus aureus ST672-MRSA-IV/t1309 (an emerging disease clone) and a high prevalence of ST88-MRSA-IV/t2526 (first reports from India) was reported
  • Baseline assessment of AMR in the aquaculture farms revealed various genotypes of three major human pathogens namely, the extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli & Klebsiella pneumoniae, and the methicillin-resistant Staphylococci.
  • Comprehensive genotyping of the methicillin-resistant Staphylococcus aureus (MRSA) isolates revealed high prevalence of ST772-t345-SCCmec V, a community-associated epidemic clone.
  • Twenty-seven β-haemolytic V. parahaemolyticus were isolated from 7 out of 40 farms studied. Among the 27 isolates, 15 possessed the tdh gene and 4 had trh. ERIC PCR and PFGE illustrated the presence of pathogenic isolates that shared genetic similarity with clinical strains.
  • Quorum quenching ability of Bacillus spp. strains to reduce the expression of some virulence factors of a shrimp pathogen, Vibrio harveyi revealed the potential application of AHL-degrading Bacillus spp. as an alternative to antibiotics in shrimp hatcheries to control luminescent vibriosis
  • Shrimp shell waste bioprocessed with protease producing Bacillus strains were able to produce chitin ranging from 2
  • MLST sequence types, ST 1510 and ST 3765 were identified from Salmonella Paratyphi B isolated from seafood markets of Cochin region
  • Carbon dot synthesized from fish protein hydrolysate showed antibacterial activity against E. coli, Bacillus subtilis, Staphylococcus aureus and Methicillin resistant S. aureus
  • Fluorescent signals of the bacterial cells were found to be high during bacterial attachment to carbon dot which can be used for fluorescent imaging of bacteria
  • Silver nanoparticles synthesized using green technology with limon peel extract (Citrus limon) ntibacterial properties against V. mimicus at very low concentrations
  • Metal nanoparticles viz. Zinc oxide nanoparticles, Cupric oxide nanoparticles, and Magnesium Oxide nanoparticles were prepared by the sol-gel method it antibacterial activity was evaluated.
  • Food waste including fishery waste were converted to compost in 80 days using Bacillus subtilis and Bacillus licheniformis
  • Phage based biocontrol for E. coli and Vibrio harveyi were developed and whole genome sequencing of coliphage and vibrio phage were completed
  • Antimicrobial resistance (AMR) burden in Escherichia coli of Vembanad Lake, Kerala, revealed multidrug resistance in 30% of the strains, and extended spectrum β-lactamase (ESBL) producers in 32% of the strains

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